RedHill Biopharma Late-Breaking Abstract on Positive Phase III Crohn’s Disease Study with RHB-104 to be Presented at UEG Week 2018
The presentation will highlight data from the MAP US Phase III study of RHB-104, including subgroup analysis of treatment with and without anti-TNF agents. Positive top-line results from the MAP US Phase III study were announced in
“As additional data from the MAP US Phase III study becomes available, we continue to learn more about the efficacy and safety of orally-administered RHB-104 and its potential to address significant unmet medical needs in Crohn’s disease,” said
The late breaking abstract, entitled ‘Phase III Randomized, Double Blind, Placebo-Controlled, Multicenter, Parallel Group Study To Assess The Efficacy And Safety Of Add-On Fixed-Dose Anti-Mycobacterial Therapy (RHB-104) In Moderately To Severely Active Crohn's Disease (MAP US)’ will be presented by Professor
RHB-104 is a proprietary, orally-administered antibiotic combination therapy, with potent intracellular, antimycobacterial and anti-inflammatory properties, with positive top-line results from a first Phase III study. RHB-104 was developed based on the hypothesis that Crohn’s disease is caused by Mycobacterium avium subspecies paratuberculosis (MAP) infection in susceptible patients. The development of RHB-104 is consistent with the growing awareness of the possibility that a bacterially-induced dysregulated immune system may contribute to the pathogenesis of various autoimmune diseases of unknown etiology. Positive top-line results from the first Phase III study with RHB-104 in Crohn’s disease (the MAP US study) were announced in
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Source: RedHill Biopharma Ltd.